[CCoE Notice] Industrial Engineering Seminar

[Tekin, Eylem]

INDUSTRIAL ENGINEERING SEMINAR

Date: January 18, 2013
Time: 10am-11am
Place: D 102


Generalized Inverse Optimization with Application to Radiation Therapy

Timothy Chan
Assistant Professor, Mechanical and Industrial Engineering
University of Toronto

Abstract


Current clinical approaches to radiation therapy treatment design typically involve trial-and-error parameter tuning in the underlying optimization problem.  We develop a generalized inverse optimization methodology to determine objective function weights in a multi-objective radiation therapy treatment planning problem and characterize the structure and geometry of optimal solutions.  Using clinical prostate cancer cases, we demonstrate that our inversely optimized treatments are comparable to clinical treatments, but can be generated using fewer, more intuitive objective functions and weights. This approach has the potential to streamline the planning process and guide the design of future treatments.


Biography

Timothy C. Y. Chan is an Assistant Professor in the department of Mechanical and Industrial Engineering at the University of Toronto. His primary research interests are in optimization under uncertainty and the application of optimization methods to radiation therapy, health care operations and sustainability. He received his B.Sc. in Applied Mathematics from the University of British Columbia, and his Ph.D. in Operations Research from the Massachusetts Institute of Technology. Before coming to Toronto, he was an Associate in the Chicago office of McKinsey and Company, a global management consulting firm. During that time, he advised leading companies in the fields of medical device technology, travel and hospitality, telecommunications, and energy on issues of strategy, organization, technology and operations.

-------------- next part --------------
An HTML attachment was scrubbed...
URL: http://Bug.EGR.UH.EDU/pipermail/engi-dist/attachments/20130117/3fd18c22/attachment.html