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<p class="MsoNormal"><span style="font-size:13.5pt;font-family:"Arial",sans-serif;color:black"><img width="599" height="171" style="width:6.2395in;height:1.7812in" id="Picture_x0020_2" src="cid:image001.png@01DB3FEC.55E53CC0" alt="Dissertation Defense Announcement at the Cullen College of Engineering"></span><span style="font-size:13.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none"><o:p></o:p></span></p>
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<b><span style="font-size:18.0pt;font-family:"Times New Roman",serif;color:#C8102E;mso-ligatures:none">Modeling Nanofiltration Separation Mechanisms in Covalent Organic Framework Membranes</span></b><span style="font-size:18.0pt;font-family:"Times New Roman",serif;color:#C8102E;mso-ligatures:none"><o:p></o:p></span></p>
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<b><span style="font-size:13.5pt;font-family:"Times New Roman",serif;color:black;mso-ligatures:none">Dana Flores</span></b><span style="font-size:13.5pt;font-family:"Times New Roman",serif;mso-ligatures:none"><o:p></o:p></span></p>
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<span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none">December 3, 2024; 10 a.m. – 12 p.m. (CST)<br>
Location: Room 320 Agrawal Engineering Research Building</span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
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<span style="color:black;mso-ligatures:none"><a href="https://urldefense.com/v3/__https://teams.microsoft.com/l/meetup-join/19*3ameeting_M2RjMjc4NWQtMGU0Zi00YjRmLWE0ZGItNmZhMTU5ZTgyOWU3*40thread.v2/0?context=*7b*22Tid*22*3a*22170bbabd-a2f0-4c90-ad4b-0e8f0f0c4259*22*2c*22Oid*22*3a*22287202c1-b36a-4fd5-a496-f9d68a6f6862*22*7d__;JSUlJSUlJSUlJSUlJSUl!!LkSTlj0I!APeveIFvpnXSkfKAEvQeV85Si-n7t0PFXKM-KK88cKFL3Hp0LHj7YkbhXoAlKej-831axSkGGo6AFiAeT8VhXR7A5lI$"><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:#0563C1">Virtual
Microsoft Teams</span></a></span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none">
</span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
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<b><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none">Committee Chair:
</span></b><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none"><br>
Devin L. Shaffer, Ph.D.</span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
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<b><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none">Committee Members:</span></b><span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none"><br>
Bezawit A. Getachew, Ph.D. | Stacey M. Louie, Ph.D. | William G. Rixey, Ph.D. | <br>
Surendar R. Venna, Ph.D.</span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
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<b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#C8102E;mso-ligatures:none">Abstract</span></b><span style="font-size:12.0pt;font-family:"Arial",sans-serif;color:#C8102E;mso-ligatures:none"><o:p></o:p></span></p>
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<span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none">Solute transport in nanofiltration (NF) membrane systems is described with the Donnan Steric Pore Model with Dielectric Exclusion (DSPM-DE), which couples size- and
charge-based solute partitioning mechanisms into and out of membrane pores with flow through pores, as described by the Extended Nernst-Planck equation. If membrane structural and chemical characteristics are well defined, the DSPM-DE can theoretically be
used to identify solute rejection mechanisms, predict NF performance, and guide membrane design. However, the presence of additional separation mechanisms, like adsorption, and the heterogeneous, convoluted characteristics of traditional NF membranes challenge
these goals. In this work, we apply covalent organic frameworks (COFs) as model NF membrane materials to demonstrate control over partitioning and transport mechanisms. We experimentally isolate and quantify steric and non-steric contributions to solute partitioning
and transport in NF via application of the DSPM-DE to COF membranes fabricated with tailored pore sizes and charge properties. We also demonstrate enhanced non-steric solute rejection by changing COF membrane chemistry, and we highlight the significant impact
of adsorption on measured solute rejection by COF membranes.</span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
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<span style="font-size:10.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none">Next, the knowledge gained through this modeling work is applied to estimate the removal of environmentally persistent pharmaceutical pollutants from a simulated domestic
wastewater effluent by COF NF membranes with different charge properties, a relevant separation for water recycling. Size-based rejection of uncharged pharmaceutical solutes is well-predicted by the DSPM-DE. Charge-based exclusion mechanisms are relevant for
the negatively charged solute, and its rejection by the membrane with fixed negative charges (TpPa-SO<sub>3</sub>H COF) is accurately predicted. For the nominally uncharged membrane (TpPa-1 COF), however, rejection is underpredicted. Membrane characterizations
reveal that the fixed negative charge of the TpPa-SO<sub>3</sub>H COF can be effectively screened by feed solution ionic strength. In contrast, the persistent negative charge of the TpPa-1 COF is not screened by solution ionic strength and results in enhanced
non-steric rejection over model predictions. Quantifying relative contributions of solute separation mechanisms via the DSPM-DE allows for strategic NF membrane design. Combined with independent control over pore properties afforded by COF membranes, this
knowledge drives the development of tunable, fit-for-purpose NF membranes with predictable performance for challenging separations.</span><span style="font-size:10.5pt;font-family:"Arial",sans-serif;mso-ligatures:none"><o:p></o:p></span></p>
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<p class="MsoNormal"><span style="font-size:13.5pt;font-family:"Arial",sans-serif;color:black"><img border="0" width="599" height="82" style="width:6.2395in;height:.8541in" id="Picture_x0020_1" src="cid:image002.png@01DB3FEC.55E53CC0" alt="Engineered For What's Next"></span><span style="font-size:13.5pt;font-family:"Arial",sans-serif;color:black;mso-ligatures:none"><o:p></o:p></span></p>
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