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<span style="font-size:1.0pt; color:#F4F4F4">Calling innovators aiming to optimize patient care for immunotherapies within the hematologic malignancy space.
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<span style="font-size:7.0pt; font-family:"Arial",sans-serif; color:#888B8D">Calling innovators aiming to optimize patient care for immunotherapies within the hematologic malignancy space</span></p>
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<span style="font-size:1.0pt; line-height:130%; font-family:"Arial",sans-serif; color:black"><a href="https://urldefense.com/v3/__https:/ctkRZ04.na1.hubspotlinks.com/Btc/ZR*113/ctkRZ04/VWlZ638-3HYDW8fpVV54xFNGqW8rPchQ4BPvvvN1WCR-p5nKvpV3Zsc37CgFRMW4Kms_M22WMQKW2m5k4w48Bd2TW3vGkzk3ng67zW6SxQrP1SGLpdVfxmL91bKl2SN5dfS1cyRDL6W4JGRCR6H3NLBW83rtY94prY3gVNVhNP48g6TmN7stG2Z8nxsZV-bhry76KlRYW2KWTGt3T6zXXW5R01fv7J1yczN8-BG6VNpLsxN2CyCpKdnQwyW7fHSmK61hSvrW5Kj_k03NTJ_mW2h-9Cx9jCdQxW4SBJbp1xdyX6W4dBLg71Bs4CnW4mRRNn5TDSTlW4M9p1w3_m-bHW7ZmKX-2G9WzFW5fkpYt3VPKy1V1gCz06vxQ2RW2fghcd7qz5zlW16tjbL5cwzc-W5ZyX4B7tKgLzVJfHBS7n_7kvVrxSxy1Q-jLzW78Xqc462nCBMW2RjW238Ynb_hW3TXT9c81Qj_HW2T4G8L2-bRVN38Hl1__;Kw!!LkSTlj0I!Ed0c1x7Im7dPzsx4-Z8EVi4rcuIuwNcs_ZeT-73uoXus_dwz5Zk2jqJ7COHgY1eYNxvaCKKdK1pZq4FgBQ$" target="_blank"><span style="color:black"><span style="color:#C800A1"><img border="0" width="600" id="x__x0000_i1033" alt="neurotoxicity" style="width:6.25in" src="https://hs-3988599.f.hubspotemail.net/hub/3988599/hubfs/neurotoxicity_banner_600.png?width=1200&upscale=true&name=neurotoxicity_banner_600.png"></span></span></a></span></p>
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<span style="font-size:10.5pt; font-family:"Arial",sans-serif; color:#888B8D">Submission deadline: March 18, 2022</span></p>
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<h1 style="margin: 0in 0in 0.0001pt; line-height: 120%; font-size: 18pt; font-family: Arial, sans-serif; color: black; font-weight: normal;">
Improving Detection of Neurotoxicity in Immunotherapies</h1>
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<p>Dear Shilpa,</p>
<p style="">There are new immunotherapy <a href="https://urldefense.com/v3/__https:/ctkRZ04.na1.hubspotlinks.com/Btc/ZR*113/ctkRZ04/VWlZ638-3HYDW8fpVV54xFNGqW8rPchQ4BPvvvN1WCR_V3q90JV1-WJV7Cg-dGW6x-8Jp7rxV0SW1vss8F30gs-3N62yfsfxLXtzW6pyymR7b2lw1W42lf8l8bFBkHW8NCgn31vYNMjW33NgQq3f3QP7VKR9Wg70qV31VJ-CWQ7Vt0vsVhdrkC3sY_XCW906mCM8jKmqnW6Hq5Fj8j9t6hW5Vp9L_4-XklhW6k98Zw38ls9KN2QBtWY7mF5jW2FCsf56yf8LbW8V5wV921DLNJW4VgJNZ2Z2f8sW52L3QQ8nnKF8W909_9B8j24k4W6YYpQt6XgYPyF2t4Jc1-ZrJW1zZkCR2WpBYcW1XP3912NMVB-Mg3_rYn0S22W6z3fgg5CLkH6W8lnDCm981QJdW1GvPlB1c-rxb31D01__;Kw!!LkSTlj0I!Ed0c1x7Im7dPzsx4-Z8EVi4rcuIuwNcs_ZeT-73uoXus_dwz5Zk2jqJ7COHgY1eYNxvaCKKdK1o1K2KPGQ$" target="_blank">
cancer treatments</a> available for hematologic malignancies, such as T-cell based immunotherapies and chimeric antigen receptor T-cell (CAR-T) therapies. However, some patients
<a href="https://urldefense.com/v3/__https:/ctkRZ04.na1.hubspotlinks.com/Btc/ZR*113/ctkRZ04/VWlZ638-3HYDW8fpVV54xFNGqW8rPchQ4BPvvvN1WCR_h3q905V1-WJV7CgVPRW1mbdJT70K24DW2hwp8t37rsNnW24CBHG1NFQBvW8N9wXS2Zcz8RW6Y7gsn4t0crJW6bNfs67_c8wPW2nPf5P745XGjW1PR-c34W_3nsW45TYCY5Cn_tBW96KkpQ40mHNDVlzd6Z3Wt5NwW18q7by4fbqr7W77W7J969kks3W5gHhcd8ZWmrBVkk9X825fYLjN8pzb2L93SP8W1gf5355fYbXjN9bzVvmD2rstW88cB-n7SfCtZN54mLLRm7fg6W5nxYdP2RygZ-W3XP4MZ1jGMV-W2HjPbf2Ln6x9W4ZpDQQ3h9_Yp21C1__;Kw!!LkSTlj0I!Ed0c1x7Im7dPzsx4-Z8EVi4rcuIuwNcs_ZeT-73uoXus_dwz5Zk2jqJ7COHgY1eYNxvaCKKdK1on49FTDw$" target="_blank">
experience neurotoxicity</a> as a result of treatment.</p>
<p style="">Although sometimes severe, neurotoxicity is primarily reversible and can be detected through specialized patient monitoring and care.</p>
<p style="">Johnson & Johnson Innovation is proud to launch the <b>I.D. Neurotoxicity in Immunotherapies QuickFire Challenge</b>.</p>
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<h3 style="margin: 0in 0in 0.0001pt; line-height: 120%; font-size: 15pt; font-family: Arial, sans-serif; color: white; font-weight: normal;">
Challenge rewards<sup>1</sup></h3>
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<span style="font-size:10.5pt; line-height:130%; font-family:"Arial",sans-serif; color:white">Expert mentoring<sup>2</sup></span><span style="font-size:10.5pt; line-height:130%; font-family:"Arial",sans-serif; color:black">
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<span style="font-size:10.5pt; line-height:130%; font-family:"Arial",sans-serif; color:white">Access to the JLABS ecosystem<sup>3</sup></span><span style="font-size:10.5pt; line-height:130%; font-family:"Arial",sans-serif; color:black">
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<span style="font-size:10.5pt; line-height:130%; font-family:"Arial",sans-serif; color:white">Grant funding up to increments of $200,000, $125,000, and $75,000
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Areas of Interest</h2>
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<p>Visionaries are invited to submit methods and technologies aiming to optimize patient care for immunotherapies within the hematologic malignancy space by enabling early detection of neurotoxic events. Of particular interest are technologies aiming to identify
clinical manifestations to predict acute toxicities, including movement and neurocognitive disorders.</p>
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