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<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:10.5pt; font-family:"Arial","sans-serif"; color:#1F497D">***** Seminar *****</span><span style="color:#1F497D"></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:16.0pt; color:#1F497D">Department of Electrical and Computer Engineering</span></b><span style="font-size:16.0pt; color:#1F497D"></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:16.0pt; color:#1F497D">Materials Engineering Program</span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:14.0pt; color:#1F497D">Center for Integrated Bio and Nano Systems</span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:14.0pt; color:#1F497D"> March 6, 2020</span></b><span style="font-size:14.0pt; color:#1F497D"></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:14.0pt; color:#1F497D">10:30 a.m., Room: AH108</span></b><span style="font-size:14.0pt; color:#1F497D"></span></p>
<p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:18.0pt; color:#1F497D">Integrative neural interface for brain disorders </span></b></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:18.0pt; color:#1F497D">Lu</span> <span style="font-size:18.0pt; color:#1F497D">Luan</span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:16.0pt; color:#1F497D">ECE & BioE | Neuroengineering Initiative</span></p>
<p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:16.0pt; color:#1F497D">Rice University</span></p>
<p class="MsoNormal" style=""><b><span style="color:#1F497D">Abstract</span></b><span style="font-size:11.0pt; font-family:"Calibri","sans-serif"; color:#1F497D">:</span><span style="color:#1F497D"> Brain functions and dysfunctions involve complex interactions
between neural, vascular and other cellular activities in a dynamic and long-lasting manner. This vast complexity demands the ability to simultaneously resolve multifaceted brain activities at sufficient spatiotemporal resolution, and to longitudinally track
their evolution over a long period of time. These requirements exceed the capability of any single neurotechnology. In this talk, I will discuss the development of the chronic multimodal neural interface that combines neural recording, imaging, and microstimulation,
and the opportunities it enables in studying brain disorders. I will start with the development of ultraflexible nanoelectronics threads (NETs) for scar-free tissue integration and chronically stable intracortical neural recording, which also facilitated longitudinal
optical imaging in the same brain regions. I will then demonstrate the ability to simultaneously resolve and longitudinally track hemodynamic and neural activities, and its application in a mouse model of stroke, from which we observe a substantial neurovascular
uncoupling after injury. I will conclude with our on-going development of high-resolution, chronically-stable microstimulation, and the opportunities the integrative neural interface enables for detecting, understanding, and treating a broad spectrum of neurological
and neurodegenerative disorders.</span></p>
<p class="MsoNormal" style=""><img width="185" height="185" src="cid:image003.png@01D5F165.B3B06350" align="left" hspace="12"><b><span style="color:#1F497D">Short Bio</span></b><span style="color:#1F497D">: Dr. Luan was trained as an experimental physicist.
She received her B. S. from the University of Science and Technology of China and then went to Stanford University to pursue her Ph. D. in Physics (2011). After three years at Harvard University as a postdoctoral fellow in the Physics department, she moved
to UT Austin in 2014 and made the transition to neuroengineering while being a research scientist in the department of Physics. She joined the Department of Biomedical Engineering as a research assistant professor in Sep 2017. She moved to Rice University
in Oct 2019 as an assistant professor in department of electrical and computer engineering and as part of the neuroengineering initiative.</span></p>
<p class="MsoNormal" style="text-align:justify; text-autospace:none"><span style="color:#1F497D">Contact Prof. Cunjiang Yu<a href="mailto:cyu13@Central.UH.EDU">cyu13@Central.UH.EDU</a> if you would like to meet with Prof.</span><span style="color:#1F497D">Luan.
</span></p>
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