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<span style="font-family: Calibri, sans-serif; font-size: 11pt;"> </span><span style="font-family: Calibri, sans-serif; font-size: 11pt;">SABIC Seminar Series Presents Homotypic and Heterotypic Interactions in Amyloid Protein Networks (3/22)</span></div>
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<img width="601" height="62" id="_x0000_i1031" alt="Homotypic and Heterotypic Interactions in Amyloid Protein Networks
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<img width="487" height="165" id="_x0000_i1030" alt="Regina Murphy, Ph.D.
Smith-Bascom Professor and Chair
University of Wisconsin- Madison
Friday, March 22, 2019, 10:30 am
Cemo Hall room 100D
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Amyloid protein deposits are strongly associated with the pathology observed in Alzheimer’s disease, senile systemic amyloidosis, Parkinson’s disease, and other degenerative disorders. Although the proteins in each disease differ in sequence and native fold, and all have different normal biological functions, all can be triggered to misfold and self-associate into insoluble aggregates of cross-beta structure and fibrillar morphology. Because these different proteins, upon misfolding, adopt similar conformations, we wondered whether they could interact heterotypically as well as homotypically. In this talk I will describe two examples.
Following receipt of her SB in Chemical Engineering, Regina Murphy worked for 5 years at Chevron’s Richmond Refinery before returning to graduate school. She received her Ph.D. from MIT, working under the direction of Drs. Clark Colton and Martin Yarmush, where she studied antigen-antibody complexes. She started her academic career at the University of Wisconsin- Madison in 1989, where she has been ever since. She was the recipient of the NSF Presidential Young Investigator Award and was elected as a Fellow of the American Institute of Medical and Biological Engineers. She is the author of a textbook, Introduction to Chemical Processes: Principles, Systems, Analysis, and has won several teaching awards, including the Chancellor’s Distinguished Teaching Award. She is currently serving as the R. Byron Bird Department Chair.
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Thank you,</p>
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Nicolette Solano</p>
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Administrative Assistant to M.D. Anderson Professor and Chair Michael Harold</p>
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University of Houston</p>
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Dept of Chemical and Biomolecular Engineering </p>
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Engineering Building 1, room S222</p>
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(713) 743-4304</p>
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