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<b style="mso-bidi-font-weight:normal"><span style="font-size:20.0pt;font-family:
"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">University of Houston - Biomedical
Engineering Seminar<o:p></o:p></span></b></p>
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<b style="mso-bidi-font-weight:normal"><span style="font-size:20.0pt;font-family:
"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">Friday, Dec. 7, 2018 Noon,
Rm 201 SEC<o:p></o:p></span></b></p>
<p align="center" style="text-align: center; margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<b style="mso-bidi-font-weight:normal"><span style="font-size:20.0pt;font-family:
"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;
color:#C00000"><o:p> </o:p></span></b></p>
<p align="center" style="text-align: center; margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<b style="mso-bidi-font-weight:normal"><span style="font-size:20.0pt;font-family:
"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;
color:#C00000">PHOTONIC AND
ACOUSTIC TOOLS FOR IMAGING, NAVIGATION AND ACTIVATION OF REMOTE CONTROLLED THERANOSTIC CARRIERS<o:p></o:p></span></b></p>
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<b style="mso-bidi-font-weight:
normal"><span style="font-size:20.0pt;font-family:"Calibri",sans-serif;
mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:
Calibri;mso-bidi-theme-font:minor-latin;color:#C00000"><o:p> </o:p></span></b></p>
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normal"><span style="font-size:20.0pt;font-family:"Calibri",sans-serif;
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<br>
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<b style="mso-bidi-font-weight:
normal"><span style="font-size:20.0pt;font-family:"Calibri",sans-serif;
mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:
Calibri;mso-bidi-theme-font:minor-latin;color:#C00000">D.A. Gorin,
Ph.D.<o:p></o:p></span></b></p>
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<b style="mso-bidi-font-weight:
normal"><span style="font-size:14.0pt;font-family:"Calibri",sans-serif;
mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:
Calibri;mso-bidi-theme-font:minor-latin;color:#C00000">Skolkovo Institute
of Science and Technology, Skoltech, Moscow, Russia <o:p></o:p></span></b></p>
<p align="center" style="text-align: center; margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<b style="mso-bidi-font-weight:
normal"><span style="font-size:14.0pt;font-family:"Calibri",sans-serif;
mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:minor-latin;mso-bidi-font-family:
Calibri;mso-bidi-theme-font:minor-latin;color:#C00000">Saratov State
University, SGU, Saratov, Russia<o:p></o:p></span></b></p>
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<b style="mso-bidi-font-weight:normal"><span style="font-size:20.0pt;font-family:
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mso-fareast-language:ZH-CN"><o:p> </o:p></span></b></p>
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<b style="mso-bidi-font-weight:normal"><span style="font-size:20.0pt;font-family:
"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-fareast-font-family:
"Yu Mincho";mso-fareast-theme-font:minor-fareast;mso-hansi-theme-font:minor-latin;
mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin;color:#C00000;
mso-fareast-language:ZH-CN">ABSTRACT<o:p></o:p></span></b></p>
<p style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<span style="font-size:12.0pt;
font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">The photonic and acoustic tools that can be used for in vivo navigation,
visualization and activation of new type of multifunctional carriers will be presented. These carriers will combine ability to deploy drug in controllable manner with physical triggering [1] and sensing of important biological markers [2]. Physical targeting
of carriers was realized by gradient of magnetic field [1], optical tweezers approach [3].<span style="mso-spacerun:yes">
</span>Acoustic field has a good perspectives for same purpose [4]. The carrier sensitivity to external influences as laser irradiation, ultrasound treatment [5] can be changed by variation of volume fraction and chemical composition of inorganic nanoparticles
in the nanocomposite carrier shells [1-3, 5-7]. Same approach is applied for drug delivery carriers and biosensors imaging by MRI [6], OCT [7] and photoacoustics [8] using magnetite and gold nanoparticles as contrast agents, respectively. Combination of photonic
and acoustic tools with multifunctional carriers has a good perspective for application in biomedicine for diagnostic and therapy.<o:p></o:p></span></p>
<p style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<span style="font-size:12.0pt;
font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">1. Voronin D.V. et al., ACS App. Mat. & Inter., 2017, 9, 6885<o:p></o:p></span></p>
<p style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<span style="font-size:12.0pt;
font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">2. Stetciura I.Y. et al., Cur.Opin.Pharm. 2014, 18, 149<o:p></o:p></span></p>
<p style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<span style="font-size:12.0pt;
font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">3. Stetciura I. Y. et al., Analyst, 2015, 140, 4981<o:p></o:p></span></p>
<p style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<span style="font-size:12.0pt;
font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">4. Ochiai Y.<span style="mso-spacerun:yes">
</span>et al., PLoS ONE 9(5), 2014, e97590. doi:10.1371/ journal.pone.0097590<o:p></o:p></span></p>
<p style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<span style="font-size:12.0pt;
font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">5. Korolovych V.F. et al., PCCP, 2016, 18, 2389<o:p></o:p></span></p>
<p style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<span style="font-size:12.0pt;
font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">6. German S.V. et al., PCCP, 2016, 18, 32238<o:p></o:p></span></p>
<p style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<span style="font-size:12.0pt;
font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">7.<span style="mso-spacerun:yes">
</span>Genina E.A. et al., Bio.Opt.Exp., 2016, 7, 2082.<o:p></o:p></span></p>
<p style="margin: 0in 0in 0.0001pt; font-size: 11pt; font-family: Georgia, serif;">
<span style="font-size:12.0pt;
font-family:"Calibri",sans-serif;mso-ascii-theme-font:minor-latin;mso-hansi-theme-font:
minor-latin;mso-bidi-font-family:Calibri;mso-bidi-theme-font:minor-latin">8. Yashchenok A.M.et al., J. Biophoton., 2016, 8, 792<o:p></o:p></span></p>
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