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<meta http-equiv="Content-Type" content="text/html; charset=Windows-1252"></head><body style="word-wrap: break-word; -webkit-nbsp-mode: space; -webkit-line-break: after-white-space; color: rgb(0, 0, 0); font-size: 14px; font-family: Calibri, sans-serif; "><div><br></div><span id="OLK_SRC_BODY_SECTION"><div xmlns:v="urn:schemas-microsoft-com:vml" xmlns:o="urn:schemas-microsoft-com:office:office" xmlns:w="urn:schemas-microsoft-com:office:word" xmlns:m="http://schemas.microsoft.com/office/2004/12/omml" xmlns="http://www.w3.org/TR/REC-html40"><div lang="EN-US" link="blue" vlink="purple"><div class="WordSection1"><p class="MsoNormal"><o:p> </o:p></p><p class="MsoNormal"><o:p> </o:p></p><p class="MsoNormal" align="center" style="text-align:center"><span style="font-size:10.5pt;color:black"><img width="497" height="62" id="Picture_x0020_2" src="cid:image001.jpg@01D22892.E71CDB50" alt="cid:image001.jpg@01D22892.3AA19550"></span><span style="font-size:10.5pt;color:black"><o:p></o:p></span></p><p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size: 11.5pt; font-family: Times, serif; color: black; "> </span></b><span style="font-size:10.5pt;color:black"><o:p></o:p></span></p><p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:12.0pt;color:black">Seminar<br></span></b><b><span style="font-size:14.0pt">Biomolecular Engineering for Genome Editing and Nanomedicine
<o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:14.0pt"><br></span></b><b><span style="font-size:11.5pt;color:red">Friday, October 21, 2016<br>
SEC 204: 12-1PM</span></b><span style="font-size:12.0pt;color:red"><o:p></o:p></span></p><p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:11.5pt">Speaker: Dr. Gang Bao<o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:12.0pt"><o:p> </o:p></span></b></p><p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:12.0pt"><img width="301" height="372" id="Picture_x0020_1" src="cid:image002.jpg@01D22892.E71CDB50" alt="cid:image002.jpg@01D22892.3AA19550"></span></b><b><span style="font-size:12.0pt"><br></span></b><b><span style="font-size:11.5pt">Gang Bao<o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="text-align:center"><b><span style="font-size:11.5pt">Department of Bioengineering, Rice University<o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="margin-bottom:12.0pt;text-align:center"><b><span style="font-size:11.5pt">Houston, TX<o:p></o:p></span></b></p><p class="MsoNormal"><b><span style="font-size:11.5pt">Abstract: </span></b><span style="font-size:11.5pt">The integration of biomolecular engineering, nanotechnology and biology is expected to produce major breakthroughs in medical diagnostics and therapeutics.
Due to the size-compatibility of nano-scale structures with proteins and nucleic acids, the design, optimization and application of nanoprobes, nanocarriers and molecular machines provide unprecedented opportunities for achieving a better control of biological
processes, and drastic improvements in disease detection and therapy. Recent advances include the development of engineered nucleases and multi-functional nanoparticles for biological and medical applications.
<o:p></o:p></span></p><p class="MsoNormal"><span style="font-size:11.5pt"><o:p> </o:p></span></p><p class="MsoNormal"><span style="font-size:11.5pt">In this talk I will present the design and optimization of CRISPR/Cas9 systems for treating single-gene disorders, and the development and application of multi-functional nanoparticles for molecular imaging,
cell tracking and biomolecule detection. The opportunities and challenges in nanomedicine and therapeutic genome editing are also discussed.<o:p></o:p></span></p><p class="MsoNormal"><span style="font-size:11.5pt;color:black"><o:p> </o:p></span></p><p class="MsoNormal"><b><span style="font-size:11.5pt;color:black">Bio: </span></b><span style="font-size:10.5pt;color:black"></span><b><span style="font-size:11.5pt;color:black">Dr. Gang Bao </span></b><span style="font-size:11.5pt;color:black">is the Foyt Family Chair Professor in the Department of Bioengineering, Rice University. He is also Director of Nanomedicine Center for Nucleoprotein
Machines, a NIH Nanomedicine Development Center (NDC) at Rice. Dr. Bao received his undergraduate and Master’s degrees from Shandong University in China, and his PhD from Lehigh University in the US. Dr. Bao is a Fellow of the American Association of Advancement
in Science (AAAS), a Fellow of the American Society of Mechanical Engineers (ASME), a Fellow of the American Physical Society (APS), and a Fellow of the American Institute for Medical and Biological Engineering (AIMBE).<o:p></o:p></span></p><p class="MsoNormal"><span style="font-size:11.5pt;color:black"><o:p> </o:p></span></p><p class="MsoNormal"><span style="font-size:11.5pt;color:black">Dr. Bao’s current research is focused on the development of nanotechnology and biomolecular engineering tools for biological and disease studies, including molecular beacons, magnetic nanoparticle
probes, quantum dot bioconjugates, protein tagging/targeting methods, and engineered nucleases. These approaches have been applied to the diagnosis and treatment of cardiovascular disease and cancer, and the development of gene correction approaches for treating
single-gene disorders.<o:p></o:p></span></p><p class="MsoNormal"><o:p> </o:p></p></div></div></div></span><style><!--
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