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Brain Interfaces<o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="margin-bottom:3.0pt;text-align:center;
line-height:normal"><b><span style="font-family: Cambria; ">Presented By: Ramin Pashaie, PhD<o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="margin-bottom:3.0pt;text-align:center"><b><u><span style="font-family:Cambria;
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AM <o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="margin-bottom:3.0pt;text-align:center"><b><span style="font-family:Cambria;
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2015<o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="margin-bottom:3.0pt;text-align:center"><b><span style="font-family:Cambria;
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Engineering Building 1<o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="margin-bottom:3.0pt;text-align:center"><b><span style="font-family:Cambria;
mso-ascii-theme-font:major-latin;mso-hansi-theme-font:major-latin">Electrical and
Computer Engineering Department<o:p></o:p></span></b></p><p class="MsoNormal" align="center" style="margin-bottom:3.0pt;text-align:center"><b><span style="font-family:Cambria;
mso-ascii-theme-font:major-latin;mso-hansi-theme-font:major-latin">University
of Houston</span></b><span style="font-family: Cambria; "><o:p></o:p></span></p><p class="MsoNormal" style="line-height: normal; "><span style="font-family: Cambria; ">Abstract—<o:p></o:p></span></p><p class="MsoNormal" style="line-height: normal; "><span style="font-family: Cambria; "> </span></p><p class="MsoNormal" style="line-height: normal; "><span style="font-family: Cambria; ">The brain is a large
network of interconnected neurons where each cell functions as a nonlinear
processing element. Unraveling the mysteries of information processing in
the complex networks of the brain requires versatile neurostimulation
and imaging techniques. Optogenetics is a new stimulation
method which allows the activity of neurons to be modulated by light.<o:p></o:p></span></p><p class="MsoNormal" style="line-height: normal; "><span style="font-family: Cambria; ">For this purpose, specific
cell-types of interest are genetically targeted to produce light-sensitive
proteins. Once these proteins are expressed, neural activity can be controlled
by exposing the cells to light of appropriate wavelengths. Optogenetics
provides a unique combination of features, including multimodal control
over neural function and genetic targeting of specific cell-types. These versatile
features are highly suitable for the study of the circuitry of psychiatric
and neurological disorders. The advent of optogenetics was followed by
extensive research aimed to produce new instrumentation for light delivery
or controlling light distribution inside the brain as well as neuroimaging
systems which are necessary to monitor induced activities. In this
presentation, I will summarize our recent endeavors in developing technologies
for optogenetic experiments.<o:p></o:p></span></p><p class="MsoNormal" style="line-height: normal; "><span style="font-family: Cambria; "> </span></p><p class="MsoNormal" style="line-height: normal; "><span style="font-family: Cambria; ">Biosketch—<o:p></o:p></span></p><p class="MsoNormal" style="line-height: normal; "><span style="font-family: Cambria; "> </span></p><p class="MsoNormal" style="line-height: normal; "><!--[if gte vml 1]><v:shapetype
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</v:shape><![endif]--><!--[if !vml]--><img width="118" height="163" src="cid:6F38EE2C-CC1B-48F3-9A2F-F859DA90EB83" align="left" hspace="9" alt="Description: Ramin.bmp" v:shapes="Picture_x0020_0" type="image/png"><!--[endif]--><span style="font-family: Cambria; ">Dr. Ramin Pashaie received his Ph.D. in electrical and systems engineering from
University of Pennsylvania, Philadelphia, PA, USA, in December 2007, under
supervision of Professor Nabil H. Farhat. His Thesis was focused on
understanding the mechanisms of information processing in complex networks of the
cortex. After earning his Ph.D. degree, he joined Prof. Karl A. Deisseroth lab
as a Postdoctoral Scholar in the bioengineering department at Stanford
University, Stanford, CA, USA. During his Postdoctoral training, he concentrated
on technology development for optical modulation of neural activity using the
tools of photonics and molecular genetics. In September 2009, he joined the
Department of Electrical Engineering at the University of Wisconsin–Milwaukee,
Milwaukee, USA, as an Assistant Professor and the Director of the Bio-Inspired
Sciences and Technology Laboratory (BIST-LAB), where the research is about
optical interrogation of the dynamics of large scale neural networks mostly in
the brain cortical regions. In particular, his current research interests
include implementation of neuroprosthetic devices and optoelectronic
neuroimaging instrumentation for brain machine interface applications. Dr.
Pashaie has received NSF Career Award from the Biophotonics program in Feb.
2015 and NARSAD Young Investigator Award twice in Aug. 2013 and Aug. 2015. <o:p></o:p></span></p><!--EndFragment--></div><style><!--
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p.MsoAcetate, li.MsoAcetate, div.MsoAcetate
{mso-style-priority:99;
mso-style-link:"Balloon Text Char";
margin:0in;
margin-bottom:.0001pt;
font-size:8.0pt;
font-family:"Tahoma","sans-serif";}
span.EmailStyle18
{mso-style-type:personal-reply;
font-family:"Calibri","sans-serif";
color:#1F497D;}
span.BalloonTextChar
{mso-style-name:"Balloon Text Char";
mso-style-priority:99;
mso-style-link:"Balloon Text";
font-family:"Tahoma","sans-serif";}
.MsoChpDefault
{mso-style-type:export-only;
font-family:"Calibri","sans-serif";}
@page WordSection1
{size:8.5in 11.0in;
margin:1.0in 1.0in 1.0in 1.0in;}
div.WordSection1
{page:WordSection1;}
--></style></body></html>