[CCoE Notice] Cullen College Defense Announcement- Chandra Prakash Swamy

[Hutchinson, Inez A]

[Dissertation Defense Announcement at the Cullen College of Engineering]
Removal of Pulsation Artifact From Intra-Operatively Recorded Local Field Potentials Using Sparse Signal Processing

Chandra Prakash Swamy

May 1, 2023; 10:00 AM - 11:00 AM (CST)
Location: Rm350, TIMES, HBS1
Zoom: https://urldefense.com/v3/__https://uh-edu-cougarnet.zoom.us/j/91548504307__;!!LkSTlj0I!G2G07_gdG1Z93dg_1SFnQAkfasSELoJe0p2vHaGyMjdJLXr731uRQXYVSmOJ6Bc7ujJVN8--XHfcaCyNaRyEJmaMxt4$ <https://urldefense.com/v3/__https://www.google.com/url?q=https:**Auh-edu-cougarnet.zoom.us*j*91548504307&sa=D&source=calendar&usd=2&usg=AOvVaw25ajJiDWTZUH-ZpKVP0zxI__;Ly8vLw!!LkSTlj0I!G2G07_gdG1Z93dg_1SFnQAkfasSELoJe0p2vHaGyMjdJLXr731uRQXYVSmOJ6Bc7ujJVN8--XHfcaCyNaRyE9oC3gRk$ >
Committee Chair:
Nuri Firat Ince, Ph.D.
Committee Members:
Joe Francis, Ph.D. | David Francis, Ph.D. | Ashwin Viswanathan, M.D.
Abstract
Neural recordings frequently get contaminated by ECG or pulsation artifacts. These large amplitude components can mask the neural patterns of interest and make the visual inspection process difficult. The current study describes a sparse signal representation strategy that targets to denoise pulsation artifacts in local field potentials (LFPs) recorded intraoperatively.
To estimate the morphology of the artifact, we first detect the QRS-peaks from the simultaneously recorded ECG trace as an anchor point. After the LFP data has been epoched with respect to each beat, a pool of raw data segments of a specific length is generated. Using the K-singular value decomposition (K-SVD) algorithm, we constructed a data-specific dictionary to represent each contaminated LFP epoch in a sparse fashion. Since LFP is aligned to each QRS complex and the background neural activity is uncorrelated to the anchor points, we assumed that constructed dictionary will be formed to represent the pulsation artifact mainly. In this scheme, we performed an orthogonal matching pursuit to represent each LFP epoch as a linear combination of the dictionary atoms. The denoised LFP data is thus obtained by calculating the residual between the raw LFP and its approximation.
We discuss and demonstrate a significant improvement in denoised data and compare the results with respect to principal component analysis (PCA). We noted that there is a comparable change in the signal for visual inspection to observe various oscillating patterns in the alpha and beta bands. We also see a noticeable compression of signal strength in the lower frequency band (<13 Hz), which was masked by the pulsation artifact. We also show the denoised data by using a global dictionary which was generated by leaving one subject out, where the results were not significantly different. We compare the reconstructed denoised LFP data across various methods by computing their signal-to-noise ratio (SNR) for each epoch with respect to the average of its pool.
[Engineered For What's Next]


-------------- next part --------------
An HTML attachment was scrubbed...
URL: http://Bug.EGR.UH.EDU/pipermail/engi-dist/attachments/20230426/0fadcb48/attachment-0001.html 
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image001.jpg
Type: image/jpeg
Size: 13306 bytes
Desc: image001.jpg
Url : http://Bug.EGR.UH.EDU/pipermail/engi-dist/attachments/20230426/0fadcb48/attachment-0002.jpg 
-------------- next part --------------
A non-text attachment was scrubbed...
Name: image002.jpg
Type: image/jpeg
Size: 3256 bytes
Desc: image002.jpg
Url : http://Bug.EGR.UH.EDU/pipermail/engi-dist/attachments/20230426/0fadcb48/attachment-0003.jpg