[CCoE Notice] SABIC Seminar Series Presents Homotypic and Heterotypic Interactions in Amyloid Protein Networks (3/22)

[Knudsen, Rachel W]

  SABIC Seminar Series Presents Homotypic and Heterotypic Interactions in Amyloid Protein Networks (3/22)

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[Homotypic and Heterotypic Interactions in Amyloid Protein Networks]
[Regina Murphy, Ph.D. Smith-Bascom Professor and Chair    University of Wisconsin- Madison  Friday, March 22, 2019, 10:30 am Cemo Hall room 100D]
[Amyloid protein deposits are strongly associated with the pathology observed in Alzheimer's disease, senile systemic amyloidosis, Parkinson's disease, and other degenerative disorders. Although the proteins in each disease differ in sequence and native fold, and all have different normal biological functions, all can be triggered to misfold and self-associate into insoluble aggregates of cross-beta structure and fibrillar morphology. Because these different proteins, upon misfolding, adopt similar conformations, we wondered whether they could interact heterotypically as well as homotypically. In this talk I will describe two examples.     Following receipt of her SB in Chemical Engineering, Regina Murphy worked for 5 years at Chevron's Richmond Refinery before returning to graduate school. She received her Ph.D. from MIT, working under the direction of Drs. Clark Colton and Martin Yarmush, where she studied antigen-antibody complexes. She started her academic career at the University of Wisconsin- Madison in 1989, where she has been ever since. She was the recipient of the NSF Presidential Young Investigator Award and was elected as a Fellow of the American Institute of Medical and Biological Engineers. She is the author of a textbook, Introduction to Chemical Processes: Principles, Systems, Analysis, and has won several teaching awards, including the Chancellor's Distinguished Teaching Award. She is currently serving as the R. Byron Bird Department Chair.]
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Thank you,
Nicolette Solano
Administrative Assistant to M.D. Anderson Professor and Chair Michael Harold
University of Houston
Dept of Chemical and Biomolecular Engineering
Engineering Building 1, room S222
(713) 743-4304

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